LADA — The In-Between Diabetes No One Talks About
Looks like Type 2, behaves like Type 1 — autoimmunity in slow motion.
Somewhere between Type 1 diabetes and Type 2 diabetes lives an odd hybrid — Latent Autoimmune Diabetes in Adults, or LADA. It starts like Type 2: mild symptoms, manageable with diet or tablets. But over months or years, the pancreas begins to fade, as if something deeper were wrong. That something is the immune system.
In LADA, the same autoimmune attack that causes Type 1 happens, but slower. T-cells quietly pick off β-cells over years instead of weeks. Because it develops in adults, doctors often mislabel it as Type 2. Patients might go through several medications before anyone realises they actually need insulin.
The dual nature is confusing but fascinating. Like Type 2, LADA may coexist with insulin resistance, especially if there’s excess weight or stress. Like Type 1, it’s driven by antibodies and inflammation against pancreatic cells. It’s the immune system whispering instead of shouting.
Diagnosis relies on specific antibody tests — GAD or ICA — that reveal the autoimmune fingerprints. Once identified, early insulin therapy helps preserve the remaining β-cells for longer, easing the decline.
The emotional side matters too. Many people with LADA feel whiplashed — told one day they have Type 2, then “actually it’s autoimmune.” Clarity brings peace. The label matters less than understanding what’s happening inside: a slow, quiet war that can be managed with precision and care.
Why It Matters
LADA reminds us that diabetes isn’t two boxes but a spectrum. Autoimmunity and resistance can overlap, proving that biology doesn’t follow our categories — it follows its own rhythm.
Closing Line
Not all battles roar; some unfold softly until science learns to name them.